Correction: Javed et al. The Potential Impact of Smog Spell on Humans' Health Amid COVID-19 Rages. Int. J. Environ. Res. Public Health 2021, 18, 11408.

There was an error in the original publication [...].

The Potential Impact of Smog Spell on Humans' Health Amid COVID-19 Rages.

Rapid and unchecked industrialization and the combustion of fossil fuels have engendered a state of fear in urban settlements. Smog is a visible form of air pollution that arises due to the over-emissions of some primary pollutants like volatile organic compounds (VOCs), hydrocarbons, SO2, NO, and NO2 which further react in the atmosphere and give rise to toxic and carcinogenic secondary smog components. Smog reduces the visibility on roads and results in road accidents and cancellation of flights. Uptake of primary and secondary pollutants of smog is responsible for several deleterious diseases of which respiratory disorders, cardiovascular dysfunction, neurological disorders, and cancer are discussed here. Children and pregnant women are more prone to the hazards of smog. The worsening menace of smog on one hand and occurrence of pandemic i.e., COVID-19 on the other may increase the mortality rate. But the implementation of lockdown during pandemics has favored the atmosphere in some ways, which will be highlighted in the article. On the whole, the focus of this article will be on the dubious relationship between smog and coronavirus.

Vitamin D attenuates COVID-19 complications via modulation of proinflammatory cytokines, antiviral proteins, and autophagy.

INTRODUCTION: Global emergence of coronavirus disease-19 (COVID-19) has clearly shown variable severity, mortality, and frequency between and within populations worldwide. These striking differences have made many biological variables attractive for future investigations. One of these variables, vitamin D, has been implicated in COVID-19 with rapidly growing scientific evidence. AREAS COVERED: The review intended to systematically explore the sources, and immunomodulatory role of vitamin D in COVID-19. Search engines and data sources including Google Scholar, PubMed, NCBI, Scopus, and Web of Science were used for data collection. The search terms used were Vitamin D, COVID-19, immune system, and antiviral mechanism. Overall, 232 sources of information were collected and 188 were included in this review. EXPERT OPINION: Interaction of vitamin D and vitamin D receptor (VDR) triggers the cellular events to modulate the immune system by regulation of many genes. Vitamin D operates as a double-edged sword against COVID-19. First, in macrophages, it promotes the production of antimicrobial and antiviral proteins like ß-defensin 2 and cathelicidin, and these proteins inhibit the replication of viral particles and promote the clearance of virus from the cells by autophagy. Second, it suppresses cytokine storm and inflammatory processes in COVID-19.